The second continental competition returns to the football scene after the group stage with the play-off round prior to the round of 16.
Seven of the eight teams that qualified for the round of 16 in Europe's second-tier competition were already among the top eight going into the penultimate matchday. There has only been one change in the top eight.
Eighteen matches will be played simultaneously on Thursday night to determine which teams finish in the top eight, which teams must play in the play-offs, and which teams will be eliminated from the Europa League.